glioblastoma tumor stage 4blastoma brain cancer stage 4stage 4 gbm brain cancerstage 4 brain cancer life expectancystage 3 brain tumourglioblastoma stage 4 treatmentstage 4 glioblastoma prognosisglioblastoma multiforme stage 4gbm tumor stage 4stage 4 glioblastoma life expectancyglioma stage 2glioblastoma end stage symptoms