mesothelioma metastasis sitesmesothelioma liver metastasesmesothelioma brain metastasesmesothelioma bone metastasestreatment of metastatic melanomalymphoma metastaticpulmonary metastatic diseasemalignant melanoma metastaticmetastatic endometrial adenocarcinomametastatic pancreatic carcinomaprognosis metastatic melanomametastatic esophageal cancer