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microcytic anemia vitamin deficiencymicrocytic anemia symptomssevere megaloblastic anemiaetiology of megaloblastic anemiairon deficiency anemia microcyticmicrocytic anemia pathophysiologymicrocytic normochromic anemia causesmicrocytic hypochromic anemia symptomsmicrocytic anemia thalassemiamicrocytic anemia treatment guidelinesmicrocytic anemia diagnosischronic microcytic anemia