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esophageal cancer liver metastasisesophageal cancer metastasis to brainesophageal metastasisesophageal cancer bone metastasisoesophageal cancer metastasismetastatic esophageal cancer treatmentesophageal adenocarcinoma metastasisesophageal cancer lung metastasismetastatic esophageal cancer prognosisstage 4 metastatic esophageal canceresophageal cancer spread to lungsesophageal cancer spread to brain