end stage hypertrophic cardiomyopathyend stage ischemic cardiomyopathyend stage dilated cardiomyopathyend stage cholangiocarcinomaend stage myelofibrosisend stage mesotheliomaend stages of leukemiaend stage melanomaend stage of cancermyeloma end stage symptomsend stage myelodysplastic syndromeend stage multiple sclerosis